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78% positive of 47 · Mostly Positive · Live from Steam
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S.E.M.I. is a single-player and co-op action platformer with puzzle elements. Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects!
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Review score: 78% on 2026-11-01 → 78% today (47 reviews)
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3 items on Steam, newest first.
Every build released on Steam for this game since we started tracking it, with the developer's patch notes. Updated within minutes of each new build.
We’ve added something many of you were waiting for!Steam AchievementsAchievements are now available — for escapes, failures, and questionable decisions.Steam CollectiblesNow available:8 trading cards6 badges5 emoticons3 profile backgroundsWhat’s next?We’ll kee…
Patients, attention! 🚨We have some very important news!On January 23, Side Effects May Include is officially launching into FULL RELEASE!A huge thank you to everyone who took part in Early Access and shared their feedback — you truly helped make the game bett…
Patients, attention! This is the first Early Access patch!It's been just a moment since launch, so let's call these fixes "hot on the trail." We've been gathering your feedback all weekend and have prepared a small pack of fixes.So, what's changed:📢 KEY CHANG…
ATTENTION, PATIENTS!🗓️ BIG NEWS: EARLY ACCESS DATE!Our medical staff has made a decision: on November 20th, we're officially opening the clinic doors to everyone in Early Access!Also, something interesting happened: while you were running through the corridor…
Meet the Lobby System! Now Escape is a Team Effort!We heard your feedback: assembling a full team to break out of the clinic could be challenging. To solve this, we're introducing a new feature — game lobbies!Now you can team up with random patients and fight …
ATTENTION, PATIENTS!Take your sedatives and fasten your restraint straps – our general intensive care unit is ready for your visit. The doctors haven't slept for nights, mixing the maddest ideas with a pinch of chaos to make your escape even more... interestin…
S.E.M.I. — Side Effects May Include is now fully released!Patients, we’ve officially left Early Access — S.E.M.I. is now available in its full release version on Steam.During Early Access, we put a lot of work into expanding content, improving core mechanics, …
Happy New Year, dear patients! May your escapes from the clinic be chaotic, fun, and (ideally) successful, and may your loyal, slightly brainless friends never drop you into traps at the most inopportune moment... Or at least let them do it epically - you'll h…
Patients, Attention! It's customary to sum up the results at the end of the year - and we are no exception. We want to share some fun stats with you about what you've managed to achieve in the first month since the game's Early Access release. A Few Numbers Th…
Patients, attention! The holidays are just around the corner, and along with them comes another update for our game! We’re not standing still: fixing bugs, adding new cosmetics, and making the gameplay even more engaging. Today we’ll tell you what awaits you i…
Attention, patients! We’ve carefully listened to your feedback, taken your suggestions into account, and together with you, we’re making the project better, more convenient, and more enjoyable. Below, we’ll walk you through the key changes. Therapy Course A ne…
Patients, attention! The time has come. S.E.M.I. is officially in Early Access! Buy it, gift it to friends, leave your reviews. Until November 27, the game is available with a 15% discount: https://store.steampowered.com/app/3957560/ Opening the doors to S.E.M…
Thank you to everyone who played the S.E.M.I. — Side Effects May Include demo 💊We’ve taken it offline to make way for the Early Access launch — going live today at 4 PM GMT (just 6 hours to go!) ⏰Over the past (almost) two months, more than 75,000 people play…
Patients, attention! The recent playtest has been diagnosed as “excellent.” The numbers speak for themselves - according to our doctors’ estimates, our patients have: Swallowed 9,180 pills Picked up 30,600 candies On average, you collected 100 candies per run,…
Patients, attention!The S.E.M.I. — Side Effects May Include playtest registration is now open, and we’re excited to invite you into the newest experimental build!The doors of the clinic are open — for now.It’s your turn to run, test abilities, break everything…
🚨 DEMO MODE ACTIVATED 🚨Did someone order pills? We’ve already scattered them all over the floor!The S.E.M.I. — Side Effects May Include demo is live on Steam, and now you have the chance to escape the clinic, tossing guards aside, popping pills, and tackling…
Not tested by Valve yet. Results from Valve's own testing.
Valve hasn't published test details for this game.
